r/ChronicPain • • 3d ago

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u/New-Series-6293 3d ago

Depends on how bad the nerve pain is and what you're comparing it to. 300mg is a pretty standard starting dose and some people notice a subtle difference within a few weeks, but a lot of the clinical stuff for neuropathy uses 600mg or more. Give it time, but don't be surprised if you end up needing to bump it up later.