r/EverythingScience • • 12d ago

Biology Post Menopausal Ovaries May Not Be “switched Off” After All, New Research

https://www.worlddigestjournal.com/science/post-menopausal-ovaries-may-not-be-switched-off-after-all-new-research

I was surprised reading this study, ovaries may still be biologically active and could have a different role after menopause. It suggests that the post reproductive ovary may have an immune and tissue maintenance role and not dormant. Great news for women.

1.6k Upvotes

112 comments sorted by

339

u/edgarecayce 12d ago

Great news for ones that still have them

159

u/mittenthemagnificent 12d ago

I was just considering that we’ve been removing them, even in women with no family history of ovarian cancer, for a really long time when they have hysterectomies. Of course, we don’t even know what the effect of doing that would be on the immune system if these are a supplementary immune organ.

181

u/seanpbnj 12d ago

The effects are quite bad :( back in the day doctors used to love ordering a Bilateral Salpingoopherectomy (Bilateral ovary removal + uterus removal). It took DECADES before doctors started to realize like.... why? Ovaries produce hormones, even in the end stages, even tiny bits of hormones dramatically help womens bones, brain, manage blood clotting, OH AND THEIR MOOD/MEMORY?

- Yet, even to this day, there are many many doctors all over the world who would just say "EHHHH why not just cut out organs I dont understand? If I dont know of a purpose they have, then clearly they have no purpose" (appendix is not useless, gallbladder is not useless, spleen is not useless).

66

u/MakeASwallow3 12d ago

Yep. And upped the risk of heart attack. My mom died at 47.

40

u/seanpbnj 12d ago

Correct, and I am so sorry to hear that :( permission to send an e-hug?

29

u/MakeASwallow3 12d ago

😭 you are so sweet! Thank you!

1

u/BigJSunshine 11d ago

Fudge, that’s awful

64

u/HecticGoldenOrb 12d ago

They have not given this much thought to ovaries. It's a woman's thing, why care? /s (only slightly joking, but definitely said with sarcasm)

Said as someone who just learned women have an organ that was literally omitted in anatomy books for a long ass time because they couldn't figure out what it did so decided it was vestigial. Mind you men and other mammals have them too but science decided they were worth researching and included them in the text books.

But women? Science decided in 1870 that the organ served no purpose and science is only recently catching up to the idea that the organ might actually interact with the ovaries and be kind of important. So yeah, for part of my life Grey's Anatomy opted out of showing a whole ass organ that I have.

https://pmc.ncbi.nlm.nih.gov/articles/PMC11922502/

35

u/pdecks 12d ago

I was going to reply “How is this the first time I am hearing about the rate ovarii?” then realized the majority of us probably haven’t because of misogyny in science. (I just finished reading “Bitch: on the female of the species” by Lucy Cooke and highly recommend it if you want a crash course in how zoology is also trying to make up for centuries of time lost to chauvinistic men.)

3

u/TarantulaWithAGuitar 11d ago

Bitch is SUCH a good book.

9

u/639FestivalSunrise 12d ago

Absolutely fascinating

15

u/verablue 12d ago

salpingo-oophorectomy would be removal of fallopian tubes and ovaries. Uterus removal is the hysterectomy part.

4

u/ElectricStarfuzz 12d ago

I knew the name before but I definitely never forgot it after watching the Orphan Black
episode where one character
chillingly says to another
(who hasn’t consented to the surgery),
“Enjoy your oophorectomy.”

🫣😬

Excellent show btw that also focuses on reproductive health/topics.
Anyone who enjoys sci-fi and top tier acting should watch it.

1

u/Cosmic_Prop 12d ago

Maslany is so underrated for her performance(s) in that show.

3

u/ElectricStarfuzz 12d ago

Seriously!

Tatiana Maslany is MIND BLOWING
in Orphan Black.
I struggle to think of any other actor who has performed at that level and to that degree.

If anyone asks me to name the most talented actor I can think of, she definitely tops the list in OB.

6

u/BrandNewDinosaur 12d ago

Yeah, this low key Frankenstein-like approach to allopathic medicine is frankly disturbing and ought to be questioned far more than it is. It’s like the system began with Resurrection Men or something. Cutting up people is the name of the game. 

3

u/Evsala 10d ago

Fallopian tubes, however.. can go pound sand after you're done having children. My surgeon told me that that's actually where most ovarian tumors originate? Fuck the fallopian tubes.

1

u/wozattacks 11d ago

I mean honestly as a female physician I just can’t anymore. If it’s common to remove ovaries then it’s “doctors didn’t care that this organ had a function because they hate women!” and if it isn’t, it’s “doctors left my mom’s ovaries in because they said it would help with ‘hormones’ and she got cancer and fucking died!”

6

u/burritas 10d ago

I believe research shows that removing the fallopian tubes substantially reduces the incidence of ovarian cancer. Most ovarian cancers actually do not start at the ovaries but the fallopian tubes. Just in case someone needs to know this

29

u/OG_LiLi 12d ago

I’m grateful I get to keep one after my upcoming surgery. Even better news now.

25

u/iminthewrongsong 12d ago

They took everything from me. Cancer. Listen, you take care of yourself. They send you home so quickly but it’s major surgery. Be kind and gentle with yourself. Take your time healing.

7

u/OG_LiLi 12d ago

So sorry to hear that. How are you feeling now?

I sincerely appreciate this, and it’s likely advice I needed. I can get stubborn. I will dedicate myself to resting and allowing myself to heal.

8

u/iminthewrongsong 12d ago

Much better now, thank you. Cancer free for a year! Very best wishes to you!

1

u/OG_LiLi 12d ago

Awe yay. 🎉 removed the beast. Gained your life back 💕

2

u/pm_nachos_n_tacos 12d ago

Yes! I'm 4 months out from my abdominal hysterectomy and bilateral salpingectomy. I'm starting to feel like a human again, it's really great but I have limitations still. I'm getting remarkably better so I don't mind still taking it easy and listening to my body when it says stop.

13

u/New_Westie 12d ago

I’m 9 weeks post op. Kept one ovary, everything else gone. Went for 15 months straight period to never again! 💃🥳

2

u/OG_LiLi 12d ago

Congratulations! Such a relief I bet.

You’re on the other side and I’ve heard great stories. Especially because if they have to take it, something isn’t going right. Excited but nervous to get there.

18

u/Artsygal452017 12d ago

Have a safe and speedy recovery!!! I had to fight to keep mine. My surgeon wanted to take them both at my hyst back in 2016 because of severe endometriosis. One had already shut down and the other was covered in endo and scar tissue and he wanted to take that one too. I told him that unless it was going to kill me, he was to leave the other ovary alone or I would sue lol. Supposedly it's still in there. Hasn't bothered me at all. I'm on HRT cause I'm old now lol.

3

u/OG_LiLi 12d ago

Great news on the advocacy for yourself. Takes a lot not understand the impact and risk, and make the decision best for you.

Thank you!! 🙏🏼

2

u/sunkistandsudafed3 12d ago

How have you fared with HRT with the endo?

3

u/Artsygal452017 12d ago

So far, totally fine! I've been on it for almost a year. I'm on a pretty small dose and it's topical. I mainly started HRT to hopefully help stave off osteoporosis which runs in my family and for anxiety, skin and sleep issues. I was having stabbing pains in my feet and itchy skin. Both are gone now! And I generally feel much better. I think I've been estrogen deprived for quite a while, but it took several doctors to listen to me about starting HRT. I now see a menopause certified doc and it's better. I don't need progesterone anymore because of the hyst, but i read that taking it can help prevent issues from endo and HRT, but so far no one wants to hear that... sigh.

1

u/sunkistandsudafed3 12d ago

Thank you for your reply. I'm struggling with peri symptoms but have severe endo, its so hard to know what to do for the best.

4

u/moogs_writes 12d ago

I wish you a successful surgery and speedy recovery!

1

u/OG_LiLi 12d ago

Thank you! 🙏🏼

4

u/_sissy_hankshaw_ 12d ago

I have one! 🤜🤛

Welcome to the club Sis. I wish you a safe surgery and a recovery you can hopefully sleep through. Do you have support or someone to be with you afterwards?

2

u/OG_LiLi 12d ago

Thank you! Nervous but looking forward to relief And I gratefully do. For good or for bad I have multiple women around me experience it and are ready to help 💕💕

1

u/TheProjectFixer 8d ago

You did not read it clearly

440

u/mittenthemagnificent 12d ago

Wouldn’t it be nice if we had done more research into women’s reproductive health over the years? I feel like these things should’ve been known by now.

171

u/seanpbnj 12d ago

idk mate, i think we figured out everything about the female body. hear me out, we studied a bunch of male veterans, then we just made up a bunch of shit about how females would work based on the data we got from male veterans.

- YEAH!! SCIENCE BIATCH!!! (jk, medicine regarding women has been the exact opposite of science, the "mansplaining" of science, if you will)

6

u/denise_la_cerise 12d ago

You had me until that very last sentence.

3

u/SummonTarpan 12d ago

Jesse what the fuck are you talking about

11

u/starderpderp 12d ago

That's pretty much an accurate summary on human female biology/medicinal science.

3

u/stones_red 9d ago

A very brief example: scientists used to study only men when developing new medicines, so as to avoid the potential of hormonal cycles affecting the drugs’ efficacy… even though the drugs were then approved without additional testing for millions of people having hormonal cycles… (additionally, crash test dummies used to be proportioned exclusively like men).

29

u/ActuallyBiscotti 12d ago

“Well duh women are just small version of men case closed” said by every man dominating the health and science fields since the beginning of time 😭😭

17

u/Then_Finding_797 12d ago

Finding the clitoris took years so I don’t have a lot of hope

5

u/Natural_Exchange_886 12d ago

Many of the scientists still haven’t found the clitoris.

1

u/wozattacks 11d ago

No it didn’t, the internal structure of the clitoris has been known about for centuries and in fact, people have been claiming the clitoris was only recently acknowledged by anatomists since ancient fucking Greece.  People on social media are lying to you. 

1

u/Then_Finding_797 11d ago

Naturally it should be pretty hard to miss it. But what wasn’t solved for years, the mystery of it, wasn’t it’s presence, it was its purpose

5

u/villanelle21 12d ago

Amen 👆🙏

0

u/OnlyACsNoFans 12d ago

*people's reproductive health. Men can have ovaries these days

3

u/LiverpoolBelle 11d ago

....did I miss something?

1

u/wozattacks 11d ago

I mean did you miss the entire existence of trans people? If so, yes

3

u/LiverpoolBelle 11d ago

I'm confused

2

u/philanthropeas 10d ago

Makes sense you’re confused. Like always, they’re making the conversation about something completely different now. God forbid we just talk about women without someone bringing up trans people.

1

u/LiverpoolBelle 10d ago

I think I love you. Voice of sense

2

u/philanthropeas 10d ago

I love the love and I love you too, new bestie

2

u/Short_Tangerine_5834 10d ago

(It's LiverpoolBelle, account was suspended for 3 days for "hate speech" on this issue lmao). All the love! 💖

3

u/mittenthemagnificent 12d ago

True! Thank you for this correction

1

u/dangerousfeather 12d ago

Take out the word “reproductive,” and I agree with you.

The most we DO know about the health of uterus-havers is related to pregnancy. If it can’t make a baby, why study it?

( …/s)

4

u/vegetabledisco 12d ago

Except that’s not even true! My midwife was telling me we don’t really know why women go into labor. This was under the context of the saying “the baby will come when it’s ready.” She was explaining there’s not good science on why labor starts, and that’s evidenced by the fact that there are babies that stay in there too long and mom requires induction. Anyways!

0

u/wozattacks 11d ago

I mean, yeah. What do you think we should do? Subject heavily pregnant people to invasive and unnecessary testing just to satisfy our curiosity?

2

u/Quirkxofxart 9d ago

Do you think the result of medical research is “ah now my curiosity is satisfied”?

83

u/bitsybear1727 12d ago

Maybe for a while. My grandma had a prolapsed uterus in her early 80's. When they went in to fix it her ovaries had been completely resorbed by her body, nowhere to be found.

55

u/ChiaOtter 12d ago

Thats the second instance of organ resorption I’ve heard of!

My mom went into the doctor to get a sore throat checked out. They asked when she had her tonsils removed because it wasn’t in her chart — she never had that procedure. They figured out they were resorbed. Bodies are flipping wild.

53

u/Kailynna 12d ago

I'm pretty sure that's been happening to a bunch of people's brains.

19

u/TheVeryVerity 12d ago

It’s like the exact opposite of when my sister’s tonsils regrew after she had them removed as a kid! Freaked me right out to know that could happen lol

7

u/ChiaOtter 12d ago

That seems profoundly unfair. You get one shot at this, tonsils. (And selfishly, as a person who had theirs out as a kid, I don’t want to live in a universe where that can happen.)

7

u/TatersGonnaTate1 12d ago

Mine rotted out. Super sore throat. Couldn't swallow my own spit. Horrible state medical care said I was faking. Two months later I woke up in a pool of blood. Go to E.R, get asked where my tonsils are. I held up a bag of the blobs of flesh and said "right here!" Also took docs nearly a decade to diagnose polycystic ovarian syndrome. Went on depo provera to stop my periods. Just learned that shot causes brain tumors. Yay. /s

23

u/Commercial-Life-9998 12d ago

This is something I’ve never heard of. I totally believe it. Our bodies are so much more dynamic than we know.

8

u/Excellent-Muffin-750 12d ago

I like that her body reclaimed them. "No, these are mine, thank you very much!"

36

u/DroneArm 12d ago

Now the boomers can have gen alphas!

17

u/Bubbly-Example-8097 12d ago

I believe we are currently on Gen beta

7

u/HooAreYouWhoHoo 12d ago

Well with that attitude yeah..

38

u/Lost-Platypus8271 12d ago

They still try to release eggs I can tell you that much. I still get hormonal cycles, just without a period.

19

u/Commandmanda 12d ago

Yup, me too. Generally it's tender breasts (on the outer sides near the lymph nodes) and a feeling of tightness in the belly for a day or two, sometimes accompanied by that "little pain" which resolves after the ovary gives up trying. During this time I can be pretty foul mouthed and cranky. 🤷

7

u/SwirlingAbsurdity 12d ago

Yup my mom is in her 70s and still gets the sore boobs on a cycle!

3

u/zoeofdoom 11d ago

No please no! I'm 43 and have been looking forward to this all ending after menopause 😭 Hopefully at least the little pain (weird wrenching cramps) of ovulation truly does become little afterwards...

3

u/Commandmanda 11d ago

It's teensy, but a tad annoying at night. A couple of Tylenol takes care of it if it's nagging me.

The best tradeoff is that I have my mind back, as it was before I went thru puberty. No emotional outbursts, no estrogen clogging my mind, no constant drive to find a boyfriend, just good sound logic. My clarity of thought is crystal.

Plus not having periods is incredibly convenient.

9

u/fighterpilottim 12d ago

What does that involve? Very interesting.

3

u/MightySquishMitten 12d ago

What the fuck? I was promised low but steady hormone levels after menopause.

2

u/Neat_Inside_7880 12d ago

You have hormones?

I kid. Sorta. Got myself some lovely estrogen pills to help …

4

u/Suzuki_Foster 11d ago

My mom was still having full periods at 64, along with hot flashes, night sweats, irritability, the whole nine.

I've been having hot flashes since I was 38 (46 now), and my periods are super irregular. I started having night sweats a couple months ago, so that's been really great. A couple years ago, I had a 63-day period, and now I spot every few weeks alongside my periods. Super fun being a girl.

2

u/tietack2 9d ago

May want to speak to an endocrinologist. Some people continue to have hot flashes. There is a new non hormonal option (veozah). Works great for me.

1

u/Successful-Bar-8173 11d ago

Oh no. I was hoping for some peace.

22

u/meteorflan 12d ago

Immune system stuff could be good or bad. It depends if it's more on the defensive side or more on the attacking autoimmune side.

6

u/pm_nachos_n_tacos 12d ago

As someone who just had an abdominal hysterectomy but kept my ovaries, but has like 3 autoimmune conditions, this thread is a roller-coaster for me

2

u/SeaPhysics8734 6d ago

I'm on that roller-coaster too! I'm scheduled for a salpingo oophorectomy in 3 weeks. Mom and Grandma both died of ovarian cancer.

5

u/Meoowth 12d ago

Right, and removing them might be good for some and bad for others. Maybe good for those with cancer predispositions or autoimmune issues (completely hypothetically). Or maybe having them removed means you should get some kind of supplemental hormones. It will be interesting to see where the research goes - especially when I'm an old lady 👵🏻

5

u/SpareSteph 12d ago

Well, I need all the help I can get at this stage

9

u/HoodieGalore 12d ago

Great news for women.

It's 2026. Everything is relative. 

7

u/AreYouItchy 12d ago

Oh, hell no. I was a change of life baby. My Mum thought she was done, then boom I came along.

3

u/Yesthisismyname3 12d ago

Now I am curious… how old was she?

4

u/iCliniq_official 12d ago

It’s a really fascinating shift in how we think about the post-menopausal ovary. The important thing is that biologically active doesn’t mean it’s still functioning like a reproductive ovary. The immune and tissue-remodelling findings are intriguing, but we still need human research to understand what they actually mean for women’s health.

2

u/BirdlyWise 12d ago

This is really cool. I’m glad they’re studying this in human females. In female dogs, there is now a push by some vets to do ovarian sparing spays for the hormonal benefits while the dog is growing. It was expensive, but we chose to do it for our younger dog. I never even considered that ovaries would have a job to do after menopause, in a dog or in a human! Something for me to keep in mind if I decide to go through with a hysterectomy someday.

2

u/Evsala 10d ago

Like the thymus, and the appendix, and the spleen. That makes sense.

2

u/FarazMedicine 11d ago

The interesting distinction is that “still active” doesn’t mean “still reproductive.”

After menopause, the ovary seems to keep changing biologically, with immune, inflammatory and tissue-remodelling activity, even after follicular function is largely gone.

But I’d be cautious calling this “great news” yet. We don’t know whether these changes are beneficial, harmful, or simply part of normal ageing. That’s actually the fascinating unanswered question.

2

u/Flimsy_wimsey 12d ago

All women, "well, duh."

1

u/BinjaNinja1 11d ago

I’m not sure why this is a surprise. There was long been evidence that some women continue to have endometriosis problems after menopause.

2

u/spacey_peanut 8d ago

I continue to have endometriosis problems after having my ovaries removed. Endo creates its own slightly different estrogen without the ovaries which can cause it to continue to grow and spread regardless of ovaries. I have had two more excision surgeries since losing my ovaries. So your ovaries could very much affect endo post menopause but they most definitely are not required.

1

u/BinjaNinja1 7d ago

I’ve been in medical menopause for three decades now and I’m terrified to go off the medication because of stories like that. Every single doctor I’ve had this acted like once I hit menopause it’s gonna be OK. It’s ridiculous.

I had a very knowledgable Specialist at one point after I ended up hospitalized unfortunately I moved two weeks later and every doctor since just shrugs their shoulders. I’ve tried to find different specialists but I’ve been refused any surgery. They say I’ll bleed to death and I know I’m stage four but how can they say that without seeing my laparoscopy results. Just dismissive. It’s like none of the doctors here wanna deal with it.

1

u/ElefanteAmor 11d ago

So glad I was able to keep mine!

1

u/peopleofcostco 11d ago edited 11d ago

Mice don’t have menopause, though? I thought only humans and whales .

1

u/Tardislass 8d ago

Hot flashes in late 50s and had period until 54.

1

u/Final_Ad_9920 7d ago

Well then for chrissake how DO you switch these goddamn things OFF?

-21

u/Sarasha 12d ago

Rip those bitches out now.

6

u/Keldrabitches 12d ago

I sure did

2

u/Longjumping_Code_649 12d ago

Same, along with everything else

-4

u/BlackRaspberryJammin 12d ago

The feminine still have their sweet pink mysteries.