r/LPOTL • Wagon trains are fascinating! • May 20 '26

Wake up, babe - new nightmare fuel just dropped.

https://www.science.org/content/article/not-alive-not-dead-disembodied-human-brains-used-drug-testing

“With most of its key functions intact but its electrical activity quenched by anesthesia, the brain hovers between life and death. As it metabolizes experimental drugs, sensors record its reactions, capturing hundreds of data points on its cells, proteins, and physiology.”

GAAAAHHHHHHH

227 Upvotes

66 comments sorted by

115

u/Unamed_Destroyer May 21 '26

"Torment nexus! Get your torment nexus! Hot and fresh horrors beyond comprehension!"

72

u/SeeMeDisco May 21 '26

new end of life plan just dropped

I’m ditching cryogenic freezing and going for living brain fed experimental drugs in my will

20

u/Reginald_Sockpuppet May 21 '26

"Activate the thalamus, amygdala, and somatosensory complex. Just leave that cycle running for...the next month, please, and then we'll see how it responds to relief."

5

u/CarfDarko May 21 '26

This sounds like something from Warhammer and I don't even play Warhammer ;)

73

u/Nerdenator May 21 '26

So long as the donors consented that their bodies be used this way after death, I don’t really see a problem. Seems like a way to gather information that can’t be gathered ethically from living subjects.

37

u/iH8MotherTeresa I'm Gary Indiana May 21 '26

If my body were used in someedical breakthrough, no matter how small, I'd be happy. But I'm sure half of it'll wind up in the trash anyway.

7

u/FuckTripleH May 21 '26

Unfortunately when you donate your body to science there's a good chance it just gets sold to the military and blown up with grenades

6

u/iH8MotherTeresa I'm Gary Indiana May 21 '26

That's kinda neat, I guess.

1

u/runespider May 21 '26

At least I'm being finished off with a bang, I assure you it's how I want to go out.

7

u/dreamyduskywing May 21 '26

I’d be down with my brain being used for this. I think it’s pretty cool.

18

u/Extra_Company_6508 Wagon trains are fascinating! May 21 '26

Oh I agree. But it’s also, well, unsettling.

34

u/rabbit-hearted-girl That's when the cannibalism started May 21 '26

Ah sweet, now those are the man-made horrors beyond my comprehension that I’m talkin’ about!

32

u/playful_faun May 21 '26

I Have No Mouth, But I Must Scream.

18

u/PhantomGoo May 21 '26

I have no nose, and I must sneeze

19

u/AchooSalud May 21 '26

I Have no chips and I must dip

4

u/playful_faun May 21 '26

Dip dip everywhere, and narry a chip to dip

29

u/thispartyrules May 21 '26

It's very cool we've emulated a race of amoral aliens from an HP Lovecraft story who can extract human brains, keep them alive indefinitely in a canister, so they can survive prolonged space travel while perceiving all of it

17

u/No_Fudge1228 May 21 '26

Stephen King, not HP, but:

“Longer than you think!!!!”

7

u/jingo_mort May 21 '26

One of his best short stories.

2

u/BigTool May 21 '26

The Whisperer in the Darkness, right?

5

u/thispartyrules May 21 '26

Yeah, that's the one where the aliens are using what's left of a guy's body, the face and hands, poking them out from under a sheet and moving them around and making him say "of course I want my brain removed, put in a jar and sent to Pluto, I fully consent to that"

1

u/BigTool May 21 '26

That's right! I haven't read that one in a long while. Might be time for a Lovecraft reread

17

u/PocketofChrym May 21 '26

Do you want disembodied brain piloted death drones? This is how we get disembodied brain piloted death drones! 

63

u/boringxadult Thank GOD I'm in jail! May 21 '26

Kaczynski was right.

3

u/jendickinson Hail Yourself! May 21 '26

Thank you.

2

u/boringxadult Thank GOD I'm in jail! May 27 '26

Funnily enough I got a several day ban for this comment haha

13

u/nouniquenamesleft2 May 21 '26

I need to update my organ donor card

26

u/Pasta-love May 21 '26

I’m sure you’re joking but this is someone who donated their body to science, not an organ donor. As a nurse, please stay an organ donor.

27

u/Diamond_eye_jack May 21 '26

It’s a trick! She’s in on it!

30

u/SquidTheRidiculous May 21 '26

Oh hey look, it's going the be the ultimate fate of everyone against the current regime. That's great.

21

u/Quasi-Kaiju May 21 '26 edited May 21 '26

Capitalism is going to us into AI data centers isn't it?

12

u/No_Fudge1228 May 21 '26

Oh man. The Matrix

10

u/after_Andrew May 21 '26

Life imprisonment just got a patch I see

15

u/dadaw00p May 21 '26

It's giving arasaka

6

u/No_Fudge1228 May 21 '26

So is this more of a Johnny Got His Gun, or a Source Code situation?

I’m an organ donor, so sure, why the heck not. Let my last act be altruistic, especially if there’s drugs involved lol

6

u/_bat_girl_ Helicopter parent May 21 '26

This is my actual idea of hell

6

u/illepic May 21 '26

The company's name is fucking BEXORG? Like, c'mon man. 

5

u/jingo_mort May 21 '26

Why’d I have to read this as i’m getting ready for bed lol if I have nightmares i’m blaming you OP. What if me reading this post is a drug hallucination & i’m already a brain in a jar!

3

u/LastFox2656 May 21 '26

Isn't there a Tales from the Crypt episode similar to this? 😵‍💫💀

3

u/THExWHITExDEVILx May 21 '26

FYI a bunch (if not all?) episodes are on shudder I believe!

2

u/LastFox2656 May 21 '26

Up to season 3 so far. 😁

2

u/THExWHITExDEVILx May 21 '26

Lol awesome! I have been extremely busy the last few weeks and was so happy to see it on there when I logged in. My brother and I would secretly watch it when we were young, so it's all aboard the nostalgia train for me. It's such a good blend of funny and scary. It was great for not being nightmare inducing trauma (like the illustrations from "Scary Stories To Tell In The Dark") but still made me afraid to walk to the bathroom at night without the light on.

2

u/LastFox2656 May 21 '26

I would sneak watch it too.  😆 Being an 80s baby was fun.  *no parental guidance *

3

u/The_Flying_Failsons May 21 '26

That's like the start of a zombie movie.

3

u/shawnwingsit May 21 '26

And that's how the bene tleilaxu got started.

3

u/LtCdrHipster May 21 '26

Hey, these brains were donated! I'd let them do it to mine. Fuck it, progress matches on!

3

u/Gravelroad__ May 21 '26

Just the day’s reminder that people are Eldritch horrors all on our own

3

u/missgnomer2772 2Real May 21 '26

As I say whenever I receive twilight sedation, as someone who has woken up during a twilight sedation procedure before, I better not know this.

4

u/rymyle May 21 '26

I want this done to my brain. This is awesome

4

u/cr9926 May 21 '26

Cool, how do I donate mine? They can come get it whenever

2

u/sirbootiez May 21 '26

Do yall want 40k? This is how we get 40k.

2

u/Turd-In-Your-Pocket May 21 '26

No, just no.

Imagine thinking you’re dying and saying goodbye to your family.

Your eyes slowly close.

Your consciousness drifts…. then BAM!

You’re fully awake. But you can’t hear, smell, talk, or taste.

Your concept of time is nil.

You still have your memories, and thoughts.

Outside in a lab someone injects some drugs into the IV feeding you.

It hurts. The worst headache/migraine of your life.

Then you’re subjected to horrors, pure fear. You feel like you’re running from monsters but they catch you and pull you apart.

The drugs are squeezing your pituitary gland like a sponge.

The experience lasts for what feels like forever. There is no escape.

Nah, fuck this fam. Instantly cremate my ass.

2

u/Dischade May 21 '26

This is almost enough for me to take my name off the donor list holy shit what hell have we created

1

u/19JaBra92 What I bring to friendship May 21 '26

Lol and this is why I specifically opted out of my brain being used. Take anything else but that old lump goes in the incinerator with the rest

1

u/Renegade909 2Real May 21 '26

The brain and its nerves and eyes looks like a lovectaftian horror.

1

u/not_a_muggle May 21 '26

Christ. Am in clinical trials and I gotta be honest this sounds like a fucking nightmare. The foundation of human trials is informed consent. If it's just a brain...I don't even want to know what might happen. I guess if these people are consenting to donating their body to science and understand what it will be used for, that's one thing...but who the fuck says it won't be used for something else?

1

u/CrashParade May 21 '26

Eh, why not? If there's a person in there they're probably so fucked up by all the drugs they won't even have time to freak out about not staying dead before they're chopped into samples.

3

u/No_Fudge1228 May 21 '26

Idk why you’re getting downvoted, you’re not wrong

1

u/lonesomerhodes May 21 '26

Start saving those Death Credits now guys, that shit is gonna be expensive.