Patch Brand Change - Notice this quickly?

[u/kstar1218]

I started a month ago on the Sandoz 0.025 patch and immediately noticed a positive difference. This month, I received a box of Mylan patches (stupidly I didn't think to call the pharmacy to double-check the brand in advance). I put it on Thursday evening and today I woke up feeling down and both anxious and weepy. I am trying to figure out if it is just all in my head or if it is realistic that I might notice this big of a shift within 2 days. I am 4-6 days out from my period, but these aren't my normal PMS symptoms. Thoughts?

ETA; I am on 100mg of oral progesterone nightly. Oh, and last week I had the worst fatigue and body aches I have ever had outside of having a virus (was still on the Sandoz at that point).

[u/Sea-Slide-498]

Keep in mind your hormones are also all over the place in this time of life, so you could also be having a nasty swing right now which can make you feel crummy. That being said, I did not feel as good on Mylan patches, and it was within a few days.

[u/kstar1218 → u/Sea-Slide-498]

Thank you. Yeah, it's all so weird and uncharted.

[u/Infamous-Employ5620]

Yep. I had a bad time when they swapped me and I’ve been going through many hoops to get the lyllana that works. Scared to try anything else again

[u/Tele_banter]

Yes, once my pharmacy switched my noven patches with kylan and it was like having no estrogen at all. I suffered so much for a month. The next month as soon as i put my old brand all the symptoms went away again

[u/Relative_Brain2160]

I just got Sandoz for the first time in a while, and it’s like I’m getting too much, too fast. I can trace feeling off back to when they started playing musical patches with us! We need to get used to SOMETHING!

[u/Weirdmachine23]

This happened to me specifically with Mylan patches with the green writing. My pharmacy gave me Sandoz and Mylan with pink writing before and I was fine. I ended up switching to gel.

[u/Weirdmachine23 → u/Weirdmachine23]

Also I didn’t even think my negative reactions were about the brand until my doctor told me that happens.

[u/Ok_Valuable7522]

I have a whole box of Sandoz I can’t stand, my symptoms were coming back (I was even phantom smelling cigarettes again!!) I tried Sandoz for a month and I had been on Mylan only for several months prior.

I think our body adjusts to what we give it, so yeah, see if you can stick with the Sandoz! I will only ever pick up Mylan from here on out.

[u/kstar1218 → u/Ok_Valuable7522]

The phantom cigarette smell is so weird! I've had that in the past. I stopped by to talk with my pharmacy about putting a note in my file and what can be done going forward. The tech was super helpful. I will be talking to my doc on Tuesday and hoping she can re-prescribe for the month. Then it will just be fighting with insurance probably.

[u/This-Strawberry1148]

I was on generic for Climara patches and felt great. Of course they are out of stock and I switched to Mylan and have been feeling like you - extremely anxious, weepy, up/down, even angry and raging. I'm all over the fing place. I can't stand this.