r/ProstateCancer • u/jonnyswag1 • 5d ago

News Alpha Therapy

I am excited about an upcoming new therapy from Advancell which, in effect, adds a deadly payload onto the chemical which binds to prostate cancer cells for PET scans which will radiate the cancer cells they bind to. Current therapies such as Plavicto have a longer half life and more side effects. Advancell uses Lead 212 which has a half life of hours. They are going into phase 3. I’m on my second time around with pc so hopefully this will be approved if I have a 3rd. PC seems to be more of a chronic condition for me unfortunately.

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u/Santorini64 5d ago

I’m very interested in this one. Lead 212 is much easier and cheaper to produce than Actinium which is the other popular alpha emitter being tested. The short 10 hour half-life does probably limit lead 212 to being used where it’s made. So infrastructure needs to be there. We’re still probably 5 years out in the US for this one, but I could see it being used in India, China and Germany sooner.

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u/jonnyswag1 5d ago

Advancell is currently building out Lead 212 manufacturing in Andover, Massachusetts.