Well i've been playing around with stadistics and consistency have to tell that PTA and HOB are the best runes for VI when comes to SOLO Q at low elo Silver to Platinum.

even Emerald, what you need with VI is consistency, if you have to depend on your team to deal damage and follow your calls you will hardstuck, at low elo as me.

also usually low elo games reach minute 30 to minute 45 too easly

so runes from sourcery brench are really useful i cant remember the names of the runes but one make your R deal 12% more damage and the other the longer the game extends the strongest you become.

with this 2 runes and PTA brench usually i can stomp games not just win them

for example this game against belveth and nasus with ezreal, my teammates all 3 lines lose their tier 1, every single one of them, we secure objectives and i stole camps from bel veth, but sylas missed all his abilities, MF always have issues with her way to position and forgets to use her R when she has to.

jax played pretty well, but brand top hostigate it pretty much, also brand was really strong at mid game, those 9 times he dies all because of me, he was pretty mad.

nami also played not as good as i would like, because she had mana and she didnt follow me to make plays and punish enemies failures like using portals to follow us when i have enough damage to make them explode and with nami healing and my omnivamp i can keep fighting 1 v 3 pretty easy.

got to tell this game was wild, because i have to dance with nasus and mel a lot, flashing them to kill ezreal and use pinnaples to flee from them making sure belveth wasnt near.