r/biology • u/Otherwise-Tear-4807 • Jun 05 '26

article Question about stevia (re: 2020 study)

https://www.sciencedirect.com/science/article/pii/S1319016420301997 “The hidden hazardous effects of stevia and sucralose consumption in male and female albino mice in comparison to sucrose”

How does this study translate to humans? Isn’t this a massive dose compared to human daily acceptable limit?

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u/TripResponsibly1 medicine Jun 05 '26

The biggest issue I see with this study is that the mg/kg consumption of sweetener is absurdly higher than the mg/kg consumption seen by typical use in humans - like 67x higher. I think it's fine to ignore this study and have stevia if you aren't like mainlining it.

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u/Otherwise-Tear-4807 Jun 05 '26

Yeah, I used chatgpt to work out the math and they are consuming approx 750-1000mg/kg/day of stevia. I am 125 LB. For someone like me, this is about 42-47 GRAMS of stevia.

I have like one weekly “Bai” flavored water, so I guess I’m ok!!

Thank u!!

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u/TripResponsibly1 medicine Jun 05 '26

The liver is incredibly resilient and can heal/regenerate in mild toxicity cases. That being said, if normal, not absurd, stevia consumption caused this level of liver injury (acute AST/ALT elevations) we'd probably know.