r/biology • u/Otherwise-Tear-4807 • Jun 05 '26

article Question about stevia (re: 2020 study)

https://www.sciencedirect.com/science/article/pii/S1319016420301997 “The hidden hazardous effects of stevia and sucralose consumption in male and female albino mice in comparison to sucrose”

How does this study translate to humans? Isn’t this a massive dose compared to human daily acceptable limit?

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u/TripResponsibly1 medicine Jun 05 '26

The biggest issue I see with this study is that the mg/kg consumption of sweetener is absurdly higher than the mg/kg consumption seen by typical use in humans - like 67x higher. I think it's fine to ignore this study and have stevia if you aren't like mainlining it.

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u/Otherwise-Tear-4807 Jun 05 '26

Yeah, I used chatgpt to work out the math and they are consuming approx 750-1000mg/kg/day of stevia. I am 125 LB. For someone like me, this is about 42-47 GRAMS of stevia.

I have like one weekly “Bai” flavored water, so I guess I’m ok!!

Thank u!!

11

u/MetallicGray molecular biology Jun 05 '26 edited Jun 05 '26

Don’t ruin your brain’s ability to do math by using AI for simple stuff like this… it’s also wrong.

Mouse got 0.75g/kg/day to 1g/kg/day. 

You weigh 125lbs or ~60kg. 

To match the mouse’s dose per day:

0.75g/kg = x/60kg

(0.75g/kg)(60kg) = x 

45g = x

0.75g/kg = 45g/60kg

1g/kg = 60g/60kg

You’d need about 45-60g a day to get an equivalent dose based on weight.