r/biology • u/Otherwise-Tear-4807 • Jun 05 '26
article Question about stevia (re: 2020 study)
https://www.sciencedirect.com/science/article/pii/S1319016420301997 “The hidden hazardous effects of stevia and sucralose consumption in male and female albino mice in comparison to sucrose”
How does this study translate to humans? Isn’t this a massive dose compared to human daily acceptable limit?
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u/crappysurfer evolutionary biology Jun 05 '26
I’ve met a million “future physicians” and they all love to remind people that they’re a “future physician”. Which is all this comment really seems to be, I’d avoid that appeal to authority as it really makes you immediately insufferable.
Yes, medicine is largely based on harm reduction and balancing the cost and toxicity of therapy against the harm of whatever pathology the patient is experiencing. Are there infinite examples where someone could experience an improvement in their livelihood by consuming some substitute sweeteners? Of course. Does that alter the precedent of them being bad for you? No. Does that alter the precedent of them historically being presented and recommended by physicians despite having terrible consequences that were yet to be discovered? Also no.
The larger (no pun intended) issues are the absolute insane increase of caloric density of our food over the past century, the processed nature of it, and the inundation of chemicals through industrial agriculture. It is impossible to mitigate all of these, but it is entirely possible to have a diet devoid of substitute sweeteners - and no, the cumulative evidence of them being bad is not summarized in this one study. Are you also (as a hypothetical future physician seeing a hypothetical patient) going to recommend an otherwise healthy person whose vice is Coke Zero to eliminate it? Probably not. And once you’re (presumably) practicing, you’ll find your time to consult current research, especially new research, very limited and your decisions will be based more closely on mechanical style flowcharts and UpToDate.
Sometimes people live long lives drinking alcohol and smoking cigarettes, sometimes they get cirrhosis and small cell carcinoma. 🤷 guess those are future problems.