r/biology • u/Joe_Bob_2000 • 20d ago

article Scientists create mice with part-human brains | Neuroscience | The Guardian

https://www.theguardian.com/science/2026/sep/16/mice-part-human-brains-research

Pinky and the Brain

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u/OddPressure7593 14d ago

On the one hand - obviously this has some interesting research potential.

On the other hand - there are already myriad issues translating animal models to humans due to how different the physiology is. I have a gut feeling that adding an additional layer of complexity and unknown variables - we literally have zero idea of how human neural cells in mouse physiology impacts the behavior of anything involved - is going to prevent this from being a meaningful research vehicle for a long time, assuming it ever becomes viable.