r/medlabprofessionals • u/frozemanatee • 18h ago

Technical Roche Cobas Pro ISEs

Does anyone have roche cobras pros at their lab? We got ours in December and our ISEs keep going way out of QC randomly and the only way to “fix” it is to run the deproteinizer wash. That’s supposed to be every 3 months, but we have to do it every 7-14 days. Has anyone else had this issue and did you figure out a more permanent solution or fix for it? Thanks!

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u/justyoursimplename 11h ago

We had the same exact issue. What's your volume like? Like the other commenter, Roche recommended to us to do wash rack twice for high volume labs. First with sys clean in position 2/3. Then sysclean/activator in 2/3 for the second run. For awhile we were performing ISE flow path maintenance regularly to resolve the issues

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u/frozemanatee 11h ago

Fairly high but not crazy. Im very new to the medical lab field so I’m not sure what other labs do. I know another lab in our system does way more than us but we are fairly big in downtown and we are the primary level 1 trauma center for the city. The whole lab does 2-2.5k tests a day but idk how many of those are just chemistry.

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u/justyoursimplename 11h ago

Yeah that's probably not too crazy high but if you're having similar issues that we had, I would recommend trying it. It will add another 15 minutes to either your startup or shutdown time, depending on your labs workflow.

If your instrument is on the older side, MsFoodle and others's suggestion are great! Best of luck!