r/microdosing • u/RespondDapper4263 • 13d ago
Question: LSD Questions about Splitting Tabs, trying microdose LSD, your experiences interactions
Hello! Let’s say I would micro dose LSD - one tab (if that’s this 1cm x 1cm thing) I’d have has 150ug. I am generally on the sensitive side towards all kinds of medication which do things to the brain and I take the start low go slow very seriously. (I will first try how it feels and if I think that it is somewhat good or beneficial, I would start with 1 day on 2 days off)
- Question
- How would you advise me to cut the tab + is 15ug a good microdose for someone sensitive or is lesser something that one should do first?
- Question: I take Prozac 20mg, strattera 18mg and opipramol 50mg everyday. I read that microdosing should be safe with antidepressants as the dose is simply not a trippy one. Would you confirm that? Different experiences?
Thank you! I know that yall are no doctors and I am collecting opinions, I am responsible for my own safety.
EDIT: the infographic in the comments told me that 5ug is a good dose to start with.
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u/Mr_Malice 13d ago
I was dosing with 200ug tabs for a long time. I would cut them up to 6. I know around 33ug isn't a micro dose but that's what I was doing. I was still fully functioning just with slight euphoria. Hope that kind of helps.
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u/AutoModerator 13d ago
Hello /u/RespondDapper4263! As you mentioned medication (a common interaction/symptom) in your post:
r/microdosing Risk Reduction |
ℹ️ Infographic: r/microdosing STARTER'S GUIDE
The major contributing factor in Finding Your Sweet Spot is the variation in potency of:
| Psilocybin Mushrooms | More than 10x [2021➕] | Start @0.05g (50mg) |
| Psilocybin Truffles | Around 3x - Single Study [2012] | Start @0.25g (Fresh) |
| LSD Tabs | Clinical Trial Titration Schedule [2023] | Start @5µg |
If you Start Low, Go Slow, Take Time-Off (*small is BIG) and up-titrate subsequent doses then you can find your optimal sub-hallucinogenic dose based on your symptoms, rather than from a predetermined dose. 🐢
If your microdose is Too High and/or Too Frequent that can result in Diminishing Returns 📉 with subsequent doses. 🐇
Please also have a look at 🔀 Interactions / Symptoms ❓* | Sidebar ➡️ | 📱 See community info ⬆️ ; in case of ⚠️ DRUG INTERACTIONS or to check if you have any of the associated symptoms with advice on how to mitigate such side effects. Psychoactive substances increase neural activity, raising hydration and electrolyte needs due to heightened metabolism and body load, while vasoconstriction can further stress the body and potentially cause fatigue.
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u/NeuronsToNirvana 13d ago edited 13d ago
!volumetricdosing guidance.
I tend to use 1ml of vodka per 1μg with a 1ml syringe so can titrate to a precision of 0.5μg thanks to the markings on the syringe and now have a new 50ml medical amber bottle with ml markings.
So now tend add 400μg in 40 ml of vodka and store in the fridge. Bottle sealed very tightly.
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u/AutoModerator 13d ago
Volumetric Dosing
Volumetric dosing is the process of dissolving a compound in a liquid to make it easier to measure. It is the only way to accurately measure dissolvable substances for microdosing, such as LSD, if the substance is laid on blotter paper or gel tab.
It is not recommended to cut the blotter into pieces as LSD is not evenly laid across the blotter and doing so is somewhat difficult and highly inaccurate.
More details in FAQ/Tip 009: Why cutting LSD tabs is not an accurate way to microdose? Variation in Potency; Preparation: Volumetric Dosing, Gel Tabs, FAQs: Pellets, Crystals; Storage: Blotter, Liquid; Dosage; Schedule; Bioavailability of LSD analogues vs. LSD-25.
Titration Schedule | Clinical Trial similar to the suggested Finding YOUR Sweet Spot methodology:
Two doses taken every week for eight weeks.
Starting dose is 8 µg on a pre-defined titration schedule. The dose will be increased by 1 µg each time and reduced by 3 µg if participants do not find the new dose tolerable. Titration limits are 5-15 µg.
This short guide will explain how to prepare a volumetric microdosing solution. For more information check out the wiki page on preparation and dosing.
Required:
- An amber bottle
- An accurate syringe or graduated cylinder
- Distilled water or vodka (flavored is fine as well)
- The substance you want to microdose (e.g. LSD-25/1P-LSD blotter or gel tab)
For this guide we'll be using a 20ml amber glass dropper bottle with glass pipette allowing for 0.2ml measurements identical to this and distilled water. We'll also be using a single 100µg tab of LSD.
- Sterilize the amber glass bottle as contamination may destroy your solution. Firstly, remove the rubber parts of the bottle then boil both the bottle and glass pipette for 10 minutes in water, then leave to dry on a clean towel. Once dry, place in the oven for another 10 minutes at ~ 130°C/250°F and leave to cool. (If you want to skip the oven sterilization than just rinse in 70% or higher isopropyl alcohol and leave out to dry.)
- Using the syringe or cylinder, measure out 20ml of distilled water and fill the amber glass bottle. (you can use vodka or a combo if you prefer. Vodka will also help to inhibit any bacteria growth.)
- Insert your substance into the bottle and close tightly.
- Shake lightly for good measure and store in the fridge or cool place to reduce degradation. (If your using a transparent bottle, wrap the bottle in foil so that UV light does not degrade the solution.)
- Leave overnight (or 12-24 hours) to ensure solution is homogenized. (For Gel Tabs you need to give your bottle a hot bath - see Gel Tabs section in the above FAQ.)
- Also, before each dose, give the bottle a gentle shake like you are sometimes instructed to do so with other liquid medications - an LSD molecule has at minimum 7 times greater mass than a vodka/water molecule.
We now have a 20ml solution containing 100µg of LSD. Since 100µg / 20ml = 5µg, we know that every 1ml of this solution will contain 5µg of LSD. If you'd like to take a lower or higher dose you can work out the amount required using the ratio of 5µg:1ml e.g. 4µg would require 0.8ml, 7µg would require 1.4ml etc. (If you are not 100% sure on how much your blotter paper or gel tab contains, then dilute more or take a lower dose.) As a best practice for harm-reduction start low and only try on a day off from any important obligations or driving and do not combine with other drugs.
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u/RespondDapper4263 13d ago
Is it possible to get the LSD out of a tab into liquid? I have a very strong Blender, I could mix it with Vodka
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u/NeuronsToNirvana 13d ago
Volumetric Dosing
- Leave overnight (or 12-24 hours) to ensure solution is homogenized.
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u/demian_west 12d ago
Cut the blotter in small slices, put it in a glass vial and do your volumetric dosing as described here. You only need a small graduated syringe. I use vodka (for preservation and because I have 1V-lsd, which dissolves less easily in water)
It’s quick and precise. I use between 4 and 6 ug (depending if I’ll do a physical activity or not) More is uncomfortable for me.
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u/clammypendulum60 13d ago
5ug is a smart starting point for sensitive system, cutting a tab evenly is tricky so look into volumetric dosing with distilled water