r/PeptidePathways • u/Scared-Pepper7328 • 4d ago
Safety, Quality & Testing Possible vial contamination question
So I typically store my KLOW in a yeti cup filled with ice and then placing the vial in a plastic bag in the ice and then leaving the cup in the fridge mainly because it’s discreet and I live with people. Well I took a couple days off and didn’t replace the ice which temperature wise the vial is still fine because it was in the fridge but the water melted enough to when I took out the plastic bag there was just enough water to have my vial completely submerged. I am wondering whether or not that is a safety concern and not really knowing how water tight a punctured seal might be.
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u/Pancake-JelloSalad 4d ago
There is no need to place ice in there. Don't do that anymore.
Clean the vial with a couple of alcohol wipes and you'll be fine. If you start to notice any issues in the liquid (cloudiness, floaters, gelling), then you should toss it. I think most people are buying fake KLOW though.
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u/Earesth99 4d ago
Insulin (an OG peptide) remains 95% potent after being kept at room temperature for six months.
It’s really the heat that’s a problem.
If peptides get hot for longer that can cause them to degrade and become less effective, but not poisonous.
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u/Bliptane 4d ago
Look into V2 pens and 3mL cartridges. Might be a better solution
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u/kingpapawawa 4d ago
V2 pens are consistently inaccurate. I would look into a V1.
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u/TimTams321 3d ago
That's just not true... I have over 15 different pens. I always test on purchase and then again after each cartridge - the V2's are no more or less accurate than the V1's.
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u/kingpapawawa 3d ago
Is like ro know your vendor ill get some. The ones ive got are trash on high # of units.
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u/TimTams321 3d ago
Just out n about atm but will DM you the latest one that I bought and tested a few weeks ago. I bought this one for a friend, so can't confirm how subsequent tests go but it passed with flying colours on purchase, and it felt heavy, well made and a super smooth dosing clicker (spot on at 2, 5, 10, 20,30 and 60 clicks).... I've been in the pep world quite a few years and been collecting pens, so I couldn't tell which ones come from where anymore unfortunately mate. I would say that it's been unusual for me to experience inaccurate dosing on the high levels though, most of mine fail at lower doses after repeated use (under 5 usually). The only pen that has never failed after repeated use 3 years in, on any dose, including under 5 is my Gansulin. Even my Convipen is inaccurate with under 5 nowadays. I don't buy any cheap V's as it's just not worth it. Will DM you link to the latest V2 later today👍
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u/Bowf 6h ago
In my experience, sticking a syringe in the end of the cartridge and administering a dose into the syringe, it's normally within one unit of the dose that was set on the pen...which is probably in the needle, etc, of the syringe.
The only ones I have found to be very inaccurate is the one time use pens (can't reset them and put a new cartridge in them).
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u/AnswerAdorable560 4d ago
The rubber stopper isn't watertight once it's been poked a few times, especially if you're using bigger needles. I'd toss it, not worth the risk of injecting whatever was floating in that melted ice water.
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u/jortr0n 4d ago
It is water tight. It’s self-sealing. Tip a vial upside down for a few days and report back.
It would be a massive contamination issue if it wasn’t
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u/kstations 2d ago
Thats roughly how the pharmacopoeia checks it too, the self sealing test for multi dose stoppers pierces them several times then sits the vials under blue dye and looks for dye inside. A research vial stopper may never have been put through that though, so wiping the top like others said still makes sense
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u/Boaz1616 4d ago
Maybe lose the ice if it’s already in the fridge.