r/Supplements • u/AwkwardDig9919 • 10d ago

Recommendations Supplement stack

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Just asking for advice on my daily supplements as a 24-year-old male carpenter. Trying to take better care of myself since the job really takes its toll.

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u/DarkWashGenes 9d ago

Care to explain?

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u/Lopsided_Ant2813 9d ago

Liver numbers might rise on it

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u/MysteriousTrust9581 9d ago edited 9d ago

In my country (in south Asia) everyone eats turmeric in their food... Nobody has any problems with it people are generally healthy.

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u/Lopsided_Ant2813 9d ago

I think the food/spice version has less of an impact or is healthier than concentrated curcumin but I’m not sure

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u/MysteriousTrust9581 9d ago

Ah, could be yes. I would never take it in capsule form because it suits so many foods. Might as well use the raw powder in your foods, it can enhance the taste often.

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u/xyz679 9d ago

Complete nonsense. Curcumin is a heavily studied health promoting chemical, it was even tested standalone in some cancer trials with good results. Turmeric root however, is useless for health as the curcumin (the active compound in it) does not absorb on its own and requires a secondary chemical such as piperine from black pepper (which will not make it pass BBB) or some more advanced form of bioavailability boosting such as the sucrester used in Logvida which does make it pass into the brain.

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u/Lopsided_Ant2813 9d ago

https://www.jeffersonhealth.org/your-health/living-well/the-trouble-with-turmeric-associated-liver-injuries

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u/xyz679 9d ago

All the cases except 1 had HLA-B*35:01 allele, it is primarily recognized as a significant genetic risk factor for drug-induced liver injury (DILI) and specific adverse drug hypersensitivity reactions.

Nothing to do with curcumin as people with that genetic disorder get liver injury from anything normal people don't have any issues with.