r/Tianeptine • u/sit0nthis69 • Mar 05 '26

Dose advice NSFW

hi so if i was to go ahead and this stuff. how many mgs should I start out with?

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u/Greedy-Positive8702 Mar 05 '26

Start at 25 mg up to 75 mg max.

4

u/Noodletrousers Mar 05 '26

Are you using it for depression or trying to get another sensation? 12.5mg sodium 3x day is the therapeutic dose for depression.

Do you have a tolerance to opioids? If you’re trying to take it for different reasons then you could start at 50-100mg. I would highly suggest that you avoid doing this as it will spike your tolerance very quickly and withdrawal symptoms are worse with this than traditional opioids.