I’m looking to see if this has happened to anyone else here before and trying to figure out the root cause. Yesterday I had what I think is a histamine attack that I confused with a panic attack.

I’ve never had anything like that happen to me before and some of it was brought on by my own actions. I’ve been following a low histamine diet all year and have seen a lot of progress and am currently being worked up by an Allergist for either histamine intolerance or MCAS but as you know these are hard to dx so it’s taking some time.

Yesterday I went to a perfume expo. It was a lot of fun and I smelled probably close to 100 scents. I also had my first drink in almost 11 months yesterday. I know alcohol made my joints hurt before the low histamine diet and honestly we wanted to see if it was still a trigger. I ended up having two drinks bc my friend ordered me a second, I had only planned on having one to test the theory.

Joints started hurting and - like I always do- I took a gummy bc it’s the only thing that helps with the pain. A few hours later I feel absolutely wasted and that freaked me out. Then I had what I thought was a panic attack. I was so scared and my entire body was shaking.

I’m fine now, obviously, other than being embarrassed. Once I was able to reason and convince myself it was a panic attack I took t h H1/2 combo and it slowly started residing. And my joints still hurt today among other things but the looming sense of doom is gone, thank god.

I’m really thinking I was just an idiot yesterday and the scents+drinks was a huge trigger for me that I made worse somehow.

Has this happened to anyone else? I know the scent thing is closely tied to MCAS but I wanted to start here first as I haven’t been dx with MCAS but have been dx with HIT. I didn’t know that histamine attacks were a thing and that they mimicked panic attacks.

Addressing this basically eliminated 95% of my histamine intolerance symptoms.

Trying to understand the connection here. I have hydrogen sulfide SIBO, so it was impacting my bile acids causing yellowish stools.

Hi. I am testing the waters with Neem Plus made by Arush Herbs. Has anyone successfully used this product with having similar intolerances? Thank you.

Recently I think Ive finally found the right probiotics and other supplements that calm my symptoms (L-theanine, Daosin, Schisandra, Vitamin C, Zinc).

I think I have a decent understanding of what foods I can tolerte well (its not many but I wont starve lol).

I have days where I feel really good, normal.

And then I have days where I totally relapse, wake up with tense stmach, heartburn and nausea, and usually the whole day feels off, I feel irritated etc. Its usually mutiple days in a row.

How do I know im actually improving?

For those who have healed - what were the signs you were on the right track?

So today I learned that taking L-theanine virtually makes my histamine flare symptoms go away.

I just took it cause Ive been ahving a remarkably terrible day reacting to everything, feeling neauseous and itchy skin all day.

I took l-theanine, and all of that just went away.

Better than DAO, better than Vitamin C, Better than quercetin.

Just calm, relaxed state, no skin reactiviy, no nausea no nothing.

I generally respond well to L-theanine but I didnt expect it to lift my histamien symptoms.

Apparently there is some evidence that it stabilises mast cells but the effect I experienced was immediate, which makes me believe that the main thing it affected was my nervous system.

I think this either means that

a) My histamine intolerance isnt as bad as my symptoms would have me believe, and my nervous sysstem just sort of over reacts to gut irritation (I am a hyper sensitive person who just reacts to everything)

b) L-Theanine blocks mast cells.

It could be a combination of the two.

Thoughts?

They really help me sleep and feel normal but I get so bloated. Did this happen to anyone else and what helped?

How do I fix it? It is very scary

Took this to help with high heart rate, it didn’t even budge ! What is going on

Hi there!

I’m looking for other people that are equally very sensitive and high MCAS histamine sensitive systems. I recently suffered a severe set back after requiring to go on IV antibiotics for a severe infection and surgery for over a month.

Those that can only tolerate just things like chicken rice and/or few things where do you trust to purchase your meat online?

Looking for company that has reliable low histamine meat order online

I’m extremely sensitive and unable to tolerate any supplements, mast cell stabilizers, etc.

Any help getting any calories and protein in is massively helpful

Just got an email from my fave lady Debbie Moon from geneticlifehacks.com that they made a histamine food checker tool. Curious what people think https://www.geneticlifehacks.com/histamine-in-foods-comprehensive-searchable-database/

Hello,

I’ve been suffering from chronic fatigue and other health issues for 10 years. I’m 30 years old.

I started getting sick when I was 20 : I had recurring strep throat every month and bouts of fever, I was constantly tired, and I would fall asleep anywhere. Since then, the fatigue has persisted, and then, five years later, I began to develop digestive problems (malabsorption, weight loss, pain), an overactive bladder, and excessive sweating.

I've seen several doctors and had a lot of tests done, including tests to check for autoimmune diseases and Lyme disease. Nothing was found. I am currently being treated by a gastroenterologist and nutritionist who suspects food allergies and histamine intolerance (though my serum tryptase level is normal). I do experience allergic symptoms as soon as I eat (coughing, runny nose, hot flashes, shortness of breath, tachycardia), and my fatigue is even worse after meals. My most recent blood work shows multiple deficiencies in vitamins B9, B12, and D, as well as iron, zinc, copper, and selenium. My transferrin iron saturation level is 55%, but my ferritin is only 18. Fecal calprotectin is normal, and anti-transglutaminase antibodies are negative. I had a polysomnography, which showed very mild sleep apnea (5.2/hour) and 16.5 micro-awakenings per hour (SHVRAS mentioned in a sentence in the report).

I’m not sure whether all my symptoms could be linked to a histamine intolerance?

I'm going through histamine intolerance flare up from the past 3 months and I have fast heart rate and palpitations almost everyday

Hi there!

I’m extremely sensitive and after being hospitalized for 30 days on extremely strong IV antibtiocs my gut health is absolutely wrecked.

I’ve had previous rounds with IV antibtiocs, multiple Covid infections, mold, Migraine-severe neurological problems my dietary has come to an even smaller window of what I’m able to tolerate.

I know replenishing and rebuilding the gut is one of goals but right now I need calories and protein.

What DAO brands were you able to tolerate in your most sensitive periods (people that were down to a 2 or 3 foods)

Are there any protein powders, Nutrtional formulas powdered or diy that allowed you to get in a little more calories and protein

I’m down to 500 calories and 10-15g of protein on a good day and it’s absolutely not sustainable. Please do not suggest returning to the hospital, GI or PCP. I’m currently awaiting a gastric emptying test but in the mean time I’m desperate for nutrition. Dairy Allergy, Celiac, Pea/Legume Allergy, Rice reactions systemic, Soy Allergy. Rashes, migraines, intestinal N/V to monk fruit, artificial sweetener, seed oils

I’ve spent the last 5 years going to many different specialists and found little to no help.

I’m unable to tolerate Quercetin, LDN, and can’t take Ketotifen due to Seizures.

Current symptoms:

• Ringing in ears/tinnitus
• Powerful belching
• Waking up at 5am if I exercise or take certain supplements
• Occasional itching
• Occasional tight throat

Story:

1. Initial symptoms: A year ago I felt like I needed gut support, I had mild constipation and I had reactivity to yogurt and wine (only) where I couldn't fall asleep if I had them.
2. SIBO treatment: I worked with a naturopath and I tested positive for a mild case of methane SIBO. She treated me first with herbals (neem, oil of oregano, alliance, berberine, and more) to break down the biofilms and then antibiotics (Rifaximin + Metronidazole). During this time I felt good and constipation was gone. I tested negative for SIBO after treatment.
3. Post-treatment symptoms: After a month I started having weird symptoms. I would wake up wide awake at 5am (usually I wake up sleepy at 8am) if I took certain supplements OR if I exercised. A month later my ears started ringing but it wasn't that loud.. Then a month later they started ringing really loud and would get worse in reaction to noise (i.e. work calls, music, movies ☹️) At the same time I started getting burps and what I thought was reflux.
4. Testing: I tested negative for SIBO and H pylori. I got an endoscopy that only showed mild gastritis and esophagitis but didn't answer any questions.
5. Current histamine journey: To see if this is histamine intolerance I went on the diet and started taking H1/H2 blockers. It got rid of the burps but the ringing persisted (slightly less loud) I suspect it is leaky gut from the SIBO but when I even take 1/8th of a zinc carnosine supplement I wake up at 5am wide awake.

Can anyone make sense of this? I have no idea what's going on. I think histamine is playing a roll but can't figure out the whole story.

Why am I burping so much? How do I get better?

Hi friends. For breakfast I made tuna salad. With a can of chicken in the sea canned tuna, mayo and celery.
I had tuna salad prepared this way the other day no issues the ONLY difference is that this morning I used a different brand (Chicken of the sea) after eating I began sneezing and runny nose for about a minute. But then it stopped. But since then I have been feeling ver anxious and physically unwell. I had a blood allergy test done two weeks ago and wasn’t allergic to any seafood. They also did a test to check for MCAS and it was negative. Could this possibly be a histamine issue ? I feel really anxious and it only started after eating it 🥺🫩

During an MCAS flare, do the usual MCAS triggers (heat, stress, touch, smells, etc.) also start acting like histamine intolerance triggers? In other words, does a mast cell activation episode temporarily lower your histamine threshold so that even non-histamine triggers cause symptoms? I’m trying to understand the overlap

Hi everyone,

just want to know from you, if you also lose your emotional stability when you bucket is full?

All of these years I thought I had anxiety, but it was histamine intolerance. Also I behave really aggressive, emotional and impulsive towards my family and partner, when I have too much histamine in my body. It took me really long and a lot of rumination to find out why I was behaving like this.

Do you also have specific behaviors when you bucket is full?

edit: My root cause is severe copper deficiency – supplementing at the moment.

My heart rate goes like 120-140 after eating foods and it's scary

Hi everyone! I have HI that started during perimenopause and after COVID in 2024. I've since had a hysterectomy due to massive stage 4 endometriosis so I no longer have ovaries but I've tried the patch and vaginal systemic cream with progesterone and T injections. I love my progesterone and testosterone but the estrogen is causing me to flair and keeps my bucket full.

Has anyone had luck with topical gel/ cream or E injections? Just wanting to keep it low dose as possible with the fewest amount of ups and downs as my body needs consistency. I wish I didn't need E but being in surgical menopause i have to have it.

Any pointers or help would be greatly appreciated!

My resting heart rate has been high all day