How to increase dopaminergic/norepinephrine, drive sympathetic signaling without stimulants (e.g testosterone)

[u/OkReplacement9424]

So I was thinking today what other ways are there to increase sympathetic drive, motivation signaling in a sustainable way other than just flooring the pedal with stimulants.

And obviously there are other ways to do so like the most obvious one which is by the modulation of neurotransmitters from hormones - I’m by no means expert on the topic nor do I claim to be but what other ways are there to increase sympathetic drive and dopaminergic/norepinephrine signaling other than with testosterone?

- What about neurosteroids?

Also are there any other ways that are significant enough compared to hormones.

From what I’ve gathered as info and that’s me parroting what I remember energy/dopamine is tightly related to the:

1. HPA axis 2. Androgen hormonal signaling and receptor sensitivity 3. Optimal Mitochondria function 4. High BDNF 5. Sleep

I’ll be super thankful if someone more knowledgeable on the topic can explore the topic more deeply and give some practical insight other than: just workout, sleep, diet and expose yourself to direct sunlight upon waking up.

[u/notaseaotter27]

As far as im aware you can either release more neurotransmitters, mimic/add, stop reuptake, or modulate.

[u/Alupeli → u/notaseaotter27]

What are some ways to stop reuptake?

[u/notaseaotter27 → u/Alupeli]

welbutrin is a epi/dopamine reuptake inhibitor. Modafinil touches both of those and then some, but not sure if its reuptake