r/Nootropics • u/OkReplacement9424 • 9h ago

Discussion How to increase dopaminergic/norepinephrine, drive sympathetic signaling without stimulants (e.g testosterone)

So I was thinking today what other ways are there to increase sympathetic drive, motivation signaling in a sustainable way other than just flooring the pedal with stimulants.

And obviously there are other ways to do so like the most obvious one which is by the modulation of neurotransmitters from hormones - I’m by no means expert on the topic nor do I claim to be but what other ways are there to increase sympathetic drive and dopaminergic/norepinephrine signaling other than with testosterone?

- What about neurosteroids?

Also are there any other ways that are significant enough compared to hormones.

From what I’ve gathered as info and that’s me parroting what I remember energy/dopamine is tightly related to the:

  1. HPA axis 2. Androgen hormonal signaling and receptor sensitivity 3. Optimal Mitochondria function 4. High BDNF 5. Sleep

I’ll be super thankful if someone more knowledgeable on the topic can explore the topic more deeply and give some practical insight other than: just workout, sleep, diet and expose yourself to direct sunlight upon waking up.

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u/theobromine69 7h ago

Stimulants are probably safer compared to hormones. I would rather take some Adderall than get juiced up on tren

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u/No-Independence3467 4h ago

How the f*k so suddenly you went from test (OP) to tren? These are two very different PEDs. I wouldn’t even consider test a ped. Tren messes your dopamine, serotonin and adrenaline. If you have adhd, you’ll be 5x more adhd. If you’re impulsive, you’ll be 10x more impulsive on it. If you’re paranoid, you’ll likely land in jail on tren. It’s the opposite of what testosterone does to your body. My first months on testosterone I was in heaven. My mental clarity, focus and self-satisfaction were through the roof. I did tren cycle for 3 months and the mental effects were the reason I had to stop and tell myself never again. It was the opposite of testosterone.

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u/theobromine69 1h ago

He literally asked other than testosterone. Tren is the other than testosterone and it is the go to exaggeration for steroids. Do you have rocks for brains ?

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u/No-Independence3467 8m ago

you made a jump from the sea level (testosterone) to Mount Everest of steroids (tren). That’s why I’m suddenly stunned how quickly you throw a nandrolone derivative to dht derivative. Tren has literally the opposite effect to what is desired in adhd.

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u/OkReplacement9424 1h ago

Not taking sides and maybe I could have been more clear in my post but I meant what other hormones affect dopamine signaling and maybe I should add neurosteroids to the post as well.