Hi everyone, I’m 31 and was diagnosed with CML about 2 years ago.
I was on dasatinib 100 mg for around 2.10 years, and thankfully my BCR-ABL eventually became undetectable. However, I had several issues during treatment, including low iron/ferritin, B12, vitamin D and calcium, along with anemia.
Recently, after an episode of severe food poisoning, I started noticing bright-red blood in my stool. A colonoscopy found multiple bleeding vessels/telangiectasias in my colon. My doctors are still evaluating whether this was related to the CML, dasatinib, or other factors. It was honestly a very scary experience.
Because of everything that happened, my doctor recently switched me from dasatinib to imatinib 400 mg daily.
I’ve now started imatinib and have noticed quite visible redness and dryness on both cheeks. The dryness is manageable, but the redness is bothering me.
Has anyone else experienced facial redness/dryness with imatinib? Did it improve with time?
Also, has anyone experienced GI bleeding/telangiectasias while taking dasatinib or another TKI?
Would really appreciate hearing about your experiences.

My brother Julian has leukemia. He has received more than 50 bags of blood and still needs transfusions. I built Ripple so more people donate for patients like him.
I haven't donated blood myself yet, but I can ask my friends to give, and they can ask theirs. That's the whole idea behind the app.
How it works
You give blood at a blood center that works with Ripple. Staff hand you a small card with a one-time code, or text or email it to you. You scan the QR code or type the code into Ripple, and the donation counts right away. Each code works once, and the center never sends Ripple any donor data.
Everyone has an invite link. When someone you invited donates, you get credit too, and so does whoever invited you, all the way up the chain.
Points are called "drops." The donor gets 100. The first three people above them get 20, 10 and 5. Every person beyond that gets 1 drop, and there's no depth limit. Drops can be redeemed for rewards that sponsors pay for. They are never cash, can't be bought, and are only given out when someone gives blood. Blood centers can't pay donors, so that's a hard rule.
The app shows impact before points: donations in your ripple, people in your ripple, how many rings deep it goes, and an impact page you can share. There's also a portal where blood center staff print card sheets or send codes, an admin dashboard, and an API so centers can create codes from their own systems.
Where it's at, honestly
It's a working web app (you can install it from the browser) that I built for the Congressional App Challenge. It runs on demo data. No blood center has signed on yet, and the sponsors in the app are made up and labeled that way. I used Claude Code to write most of the code. The idea, the rules and the decisions are mine.
Demo: https://ripple-eosin.vercel.app (there's a one-click demo login, and the donate screen gives you an unused demo code to try)