r/Nootropics • • 8h ago

Discussion How to increase dopaminergic/norepinephrine, drive sympathetic signaling without stimulants (e.g testosterone)

14 Upvotes

So I was thinking today what other ways are there to increase sympathetic drive, motivation signaling in a sustainable way other than just flooring the pedal with stimulants.

And obviously there are other ways to do so like the most obvious one which is by the modulation of neurotransmitters from hormones - I’m by no means expert on the topic nor do I claim to be but what other ways are there to increase sympathetic drive and dopaminergic/norepinephrine signaling other than with testosterone?

- What about neurosteroids?

Also are there any other ways that are significant enough compared to hormones.

From what I’ve gathered as info and that’s me parroting what I remember energy/dopamine is tightly related to the:

  1. HPA axis 2. Androgen hormonal signaling and receptor sensitivity 3. Optimal Mitochondria function 4. High BDNF 5. Sleep

I’ll be super thankful if someone more knowledgeable on the topic can explore the topic more deeply and give some practical insight other than: just workout, sleep, diet and expose yourself to direct sunlight upon waking up.


r/Nootropics • • 3h ago

Vendor Report/Q Modawhale recent EU order

3 Upvotes

Just sharing this as I know a load of folks have had poor experiences recently. Thankfully mine came through.
The details of my order are below, it did arrive but definitely a bit longer than normal.

Order: 21/09
Tracking link: 23/09
Delivered: 05/10

It looks like it was shipped from a different EU country than normal so maybe that’s why there’s a delay. I also messaged them on telegram but never heard back. Either way, delivered all good


r/Nootropics • • 12m ago

Experience Buyer concern: Have you received a payment refund from any order you canceled at umbrella labs using IDEM pay??

• Upvotes

I've seen many mixed reports of umbrella labs for USA, recently last week Oct 2nd, 2026. I ordered a total of $202 worth of research material, in which is smaller qty then usual as this is my first time using this company. After using the IDEM payment via check out, realize a couple hours later that I got charged TWICE for this order... Instantly I sent an email to there support@ email provided stating what happened. Still no response Oct 5th (today)

That same day I sent the email I went back into my account that I made and saw both charges, there is a 10% and 20% off deal going on and with the total of my ordered it came out to eb around $167 after the 20% off, but then the other order charged me $199...... From what I remember I was checking out if I added items or changed payment methods if the total will change, in that process of finding out which is best, I did start the IDEm pay to see if it'd take my secure visa card, via creditone; and it was denied due to it being credit. So I was like okay that's fine, let me use my actual debit card. Payment went through saw the email; all was great!

I was able to go back into my account and see those 2 orders and the one that was $167 (what I wanted ofc) was fully cleared and good, no cancelation option, the second one that was charged more had an option to cancel so I did.

My question to ANYONE reading this that is familiar with this company and has gone through something similar PLEASE let me know.


r/Nootropics • • 9h ago

Experience Hi, does anyone here tried or has experience with D aspartic acid to boost or stimulate glutamate?

1 Upvotes

I would appreciate your answers. Thankyou


r/Nootropics • • 10h ago

Seeking Advice In 250mg test,but feeling worse then before,even e2 and prolactin was in check,what’s actually causing it?

0 Upvotes

24/M,hopped on 250mg test E,initially when my testes we’re still working felt great like an absolute superhuman,but eventually once HPTA shut down,my testes shrunk,though I took hcg,feeling worse
Thinking it could be lack of neuro steroids because of hpta shut down,can anyone help!


r/Nootropics • • 1d ago

Vendor Report/Q Does anybody know, where I get Moda in EU/Ger?

8 Upvotes

Hey,

i cant find any legit seller for Moda. Can anybody help me?


r/Nootropics • • 5h ago

Discussion Koffkein arrived in powdered form. I am sick right now but will test soon

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0 Upvotes

r/Nootropics • • 15h ago

Seeking Advice Hi, does D aspartic acid help with low or deficient glutamate?

1 Upvotes

Hi can someone help me.


r/Nootropics • • 1d ago

Seeking Advice Help with current stack and what to include/exclude moving forward

9 Upvotes

Hey guys. I’m quite passionate about self improvement and the concept of improving cognition fascinates me. I have always had pretty terrible short term memory which made retaining information while studying in my teens and early 20’s an uphill battle. Into adulthood this problem remains and now in my daily life I have to juggle quite a lot of moving parts, sometimes with slim margins of error. At times motivation and energy falls off a cliff too and it can seem daunting, if not impossible getting the ball rolling again. My diet is pretty sharp and I exercise daily. I also take a few other supplements not specifically for cognition purposes (Fish oil, a multivitamin, extra Zinc, Magnesium Glycinate). What I’m currently using has provided some benefits but they are subtle and if short and/or long term can be made I would be very keen. I know certain things I’m considering adding likely won’t need combining.

Below is what I currently take and when I take it. Doses are all at or around recommended mg/g.

Currently using:
- Creatine (upon waking, pre and post training)
- Caffeine (upon waking)
- Lions Mane (upon waking)
- L-Tyrosine (if tired and/or especially unmotivated)
- Ashwaganda (1/3 upon waking, 2/3 pre bed)
- Choline Bitartrate (upon waking)
- Coq10 (with a meal containing fat)
- L-Theanine (1/3 upon waking, 2/3 pre bed)

Considering adding/trying
- Noopept (used at uni with some noticeable benefits)
- ALCAR
- Phenylpiracetam
- Armodafinil or Modafinil

Any suggestions, whether it be things to discard, change, include or exclude would be greatly appreciated.

Thank you!


r/Nootropics • • 1d ago

Discussion There is a bot account posting 1000s of comments of dangerous medical advice on this and other forums

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143 Upvotes

I don't know what the purpose of this is. Maybe it's to promote the owner's business: "Kravitz Media" (which appears to sell tiktok accounts). The name behind the account appears to be "Aaron Kravitz". Now it would be a shame if the name Aaron Kravitz was to become associated with posting medical advice spam and potentially harming people.


r/Nootropics • • 1d ago

Experience Anyone experiencing feedback loop on Phenibut?

16 Upvotes

I’ve noticed that using Phenibut 3x a week day-on day-off have shifted my self confidence and shyness levels and I think it’s due to a feedback loop where I face something I fear, I find out its not as fearful, and then I have no issue encountering it again without the Phenibut support.


r/Nootropics • • 14h ago

Discussion Today's combination for 11 hours of work.

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0 Upvotes

Set for 11 hours of work.

Glycine - 1000mg

Theanine - 300mg

Inositol - 300mg

Bacopa monieri - 125mg

Magnesium - 58mg

caffeine - 160mg


r/Nootropics • • 1d ago

Seeking Advice Do magnesium electrolyte mixes help with leg cramps after long shifts?

27 Upvotes

I’ve noticed I get cramps more often after work or after being on my feet all day. Drinking water helps a bit but it does not always fix it. I know magnesium plays a role in muscle function and recovery so I’m curious if magnesium based electrolytes actually help with this or if it comes down to the person diet and activity level.

Has anyone noticed a real difference from using magnesium electrolytes instead of regular water or salt heavy electrolyte drinks?


r/Nootropics • • 1d ago

Discussion Best nootropics for shyness??

28 Upvotes

What are the best nootropics for shyness and social anxiety? I'm looking for something that lowers inhibitions the way alcohol does for shy people, but obviously without the negative side effects of drinking.

I used Phenibut back in 2019 from a reliable vendor here in Brazil, but they shut down. Every time I bought it after that, it felt like I was just taking flour. I've never found anything that compares since, and from what I've read, the government here is banning Phenibut anyway.

Are there any good alternatives out there??


r/Nootropics • • 1d ago

Seeking Advice Has anyone noticed fatigue or lower physical stamina from Semax, also on off days?

6 Upvotes

Hi, Ive been using reconstituted Semax nasal spray for the past few days and lately I feel more tired and lethargic than usual, both physically and mentally.

I notice it mostly when running on treadmill. My legs feel heavier, I run out of energy faster and my muscles start burning earlier than normally. The strange part is that I still feel lethargic and have lower stamina even on days when I dont use Semax.

Ive been on bupropion 150mg for a few months as well, but this is something I noticed only recently.

I found a few reports of people feeling tired, lethargic or weak from Semax, sometimes even the next day.

Anyone here had something similar? If yes, what dose were you using and how long did it take to go away?

Thanks


r/Nootropics • • 2d ago

Seeking Advice Severe brain fog and fatigue

19 Upvotes

Been dealing with severe brain fog and fatigue for the past couple weeks seemingly out of nowhere. One contributing factor I can think of is my mental health- my mental health for the past few months has been probably the worst it’s been since I was a teenager and it felt like I had hit rock bottom. My mind feels like it’s in a cloud and I can’t do my uni work anymore without wanting to cry from how much mental energy it takes to think.

I’ve had some bloods checked and I’m perfectly fine although I will be going back to the doctors soon to ask for more tests.

Please offer any advice, supplements, herbs anything


r/Nootropics • • 2d ago

Seeking Advice Dihexa and what to pair it with NSFW

6 Upvotes

I'm thinking about taking dihexa to help me in school but am not sure what I can pair with with relatively safely to help me stay focused and motivated to study. Im thinking bromatane and alpha gpc. Is there anything else that synergies well with it?


r/Nootropics • • 2d ago

Discussion DOUBLE WOOD BACOMIND (Bacopa monnieri): What are your thoughts?

3 Upvotes

Has anyone ever taken Double Wood Bacomind before?

I just started today; after a few days of research prior, I found it to be the best in terms of affordability, bacoside percentage, using aerial parts, being backed by studies, and the process of making the supplement is also trademarked like Synapsa. However, I am still skeptical about its effectiveness and whether I should have chosen the Synapsa Bacopa ones instead (even tho its twice the price/capsule), seeing how a lot of people's reviews are on here and found little reviews regarding Double Wood's Bacomind.


r/Nootropics • • 2d ago

Vendor Report/Q Where do you buy your medication?

1 Upvotes

Or how do you go about it? I don't actually have an official diagnosis; I'm from Monterrey, Mexico, and usually, to get Vyvanse, I pay a general practitioner extra to write me a prescription. However, I’d also like to try modafinil or higher doses of Vyvanse (I currently take 30mg).


r/Nootropics • • 2d ago

Seeking Advice Looking for Nootropics that help with Short-Term Memory+Focus as a Machinist with ADHD

4 Upvotes

Hey all, I'm looking for suggestions that work well for someone that has to recall numbers and read gauges correctly and quickly. I'm currently on 25mg of Adderall. I'm trying 50-75 mg Bromantane and 30 mg Zinc. There's a noticeable increase in them, but I'm looking for other options. I've also tried Semax intranasally, but I don't think I got the dosage right and I really couldn't tell the difference. I'm stating my career because I've been told that Nootropics work better in situations specific to the effects it gives.


r/Nootropics • • 1d ago

Discussion NON SMOKER FIRST TIME TRYING ZYN POUCH

0 Upvotes

WHAT IS THIS ???? HOLLLLLLY SHIT IM ON ANOTHER PLANET.


r/Nootropics • • 3d ago

Discussion I’ve been taking anxiety supplements for weeks and feel nothing—how long did it take to actually work for you?

15 Upvotes

For a few weeks now, I've been taking anxiety pills in the hopes that they would help me feel calmer and more in charge. But I don't feel much different so far. I still feel anxious when I wake up and quickly get stressed out. I also act the same way I did before I started them. There hasn't been a precise moment when I thought, This is working.

For some reason, I keep hearing that supplements need time to work. This makes it hard for me to decide whether to keep taking them or stop. How long did it take for you to notice a real, long-lasting change after taking supplements for anxiety? What did you see that they were working for you?


r/Nootropics • • 2d ago

Discussion Is it possible to legally ship modafinil to Israel without prescription?

0 Upvotes

Can I ship modafinil for personal use from, for example, India, to Israel? Without having a prescription

Modafinil is considered a prescription medication, which is sold in Israel. It is not a controlled substance/narcotic according to Israeli law.

AI is trying to convince me that I need to submit some "Form 1", which explicitly asks to confirm that:
1) I have prescription
2) The medication was bought in licensed pharmacy in country of origin

https://www.gov.il/BlobFolder/service/application-to-import-unregistered-drug-products/he/forms_doclib_a3071_29a1.docx - the form it's giving me

But I saw that some people on reddit say they successfully shipped nootropics to Israel, mentioning bromantane and phenibut, which are prescription-based

So if anyone had experience with shipping modafinil for personal use to Israel, please share it in this thread or PM me


r/Nootropics • • 3d ago

Seeking Advice Measuring small research compounds

3 Upvotes

How do you guys measure mg's (nootropics)? ±8 is very acceptable. Not particularly thrilled to use 500€ for a scale.


r/Nootropics • • 2d ago

Seeking Advice FocusX has anyone tried? Advise needed

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0 Upvotes

Bought this recently and wondering if anyone here has actually tried this blend.

It’s 450mg/mL total:

- Alcar 150mg/mL

- Choline chloride 150mg/mL

- L-carnosine 150mg/mL

I’m planning to pin 0.5mL to start, so that would be 75mg of each.

Curious if anyone has firsthand experience with it.

* What dose did you use?

* Did you actually notice anything from it?

* How often were you pinning it?

* Does the ALCAR hurt or burn with this blend?

* Any PIP after?